Bacillus anthacis sprayed from Aum Shinrikyo headquarters building
In July 1993, a liquid suspension of Bacillus anthracis was aerosolized from the roof of an eight-story building in Kameido, Tokyo, Japan, by the religious group Aum Shinrikyo. (photographs taken July 1, 1993, by the Department of Environment, Koto-ward). [2/11/2009]
Anthrax Envelope
Photo of the anthrax-containing envelope sent to Senator Daschle. Other anthrax-containing letters had a similar appearance. [2/11/2009]
Inhalational Anthrax
This is a gross pathologic posterior oblique view of a chimpanzee's lungs that had contracted fatal inhalation anthrax. CDC PHIL [1/3/2008]
Bacillus Anthrax
Transmission electron micrograph of Bacillus anthracis. CDC PHIL [1/3/2008]
Anthrax Mediastinal Lymph Node
This is a micrograph of a mediastinal lymph node from a cynomolgus monkey, Macaca fascicularis with inhalation anthrax. CDC PHIL [1/3/2008]
Virus Extraction Phil
This 2005 photograph of the Centers for Disease Control and Prevention’s Dr. Terrence Tumpey, one of the organization’s staff microbiologists and a member of the National Center for Infectious Diseases (NCID), showed him using an electronic pipetter to extract reconstructed 1918 Pandemic Influenza Virus from a calibrated vial containing a supernatant culture medium. [1/2/2008]
H5n1 Phil
This transmission electron micrograph (TEM), taken at a magnification of 108,000x, revealed the ultrastructural details of two avian influenza A (H5N1) virions, a type of bird flu virus, which is a subtype of avian influenza A. At this magnification, one may note the stippled appearance of the roughened surface of the proteinaceous coat encasing each virion. [1/2/2008]
Biological Safety Cabinet
This photograph was taken of Dr. Taronna Maines, a microbiologist in the Influenza Branch at the Centers for Disease Control and Prevention, while she was conducting an experiment inside a biological safety cabinet (BSC) within the Biosafety Level 3-enhanced laboratory. The airflow within the BSC helps prevent any airborne virus from escaping the confines of the cabinet, and as part of her personal protective equipment, she was wearing a powered air purifying respirator (PAPR), which was filtering the air that she was breathing. [1/2/2008]
Ventilator
The need for ventilators must be anticipated if botulism is used as a bioterrorist weapon because the botulism toxins paralyze the muscles required for breathing. [2/11/2009]
Intubation in botulism
The toxin of clostridium botulinum produces muscular paralysis that can require intubation. [2/11/2009]
Clostridium botulinum spores
Botulism is the "B" of BEPAST. These are Clostridium Botulinum Bacilli, caught in the process of forming spores. They look quite similar to their relatives, Clostridium Tetani (causative agent of tetanus) and Clostridium Perfringens (causative agent of clostridial myonecrosis). The "tennis racket heads" are spores that can survive in a dry environment for years. In the right setting, they "hatch" into live bacilli and grow rapidly to produce a deadly toxin. [2/11/2009]
Wound Botulism
Wound botulism involvement of compound fracture of right arm. CDC PHIL [1/3/2008]
Infant Botulism
Six week old infant with botulism. CDC PHIL [1/3/2008]
Clostridium Botulinum
Clostridium botulinum growing on egg yolk agar showing the lipase reaction after 72 hours of incubation. CDC PHIL [1/3/2008]
Clostridium Botulinum Blood Agar
This is a Clostridium botulinum type A colony grown on a 72 hour blood agar plate; Magnification 5X. CDC PHIL [1/3/2008]
Model of Chikungunya envelope protein E1
Three dimensional model of envelope protein E1 in Chikungunya virus in position 226, indicated by the white star, could explain specific adaptation to the vector mosquito, Aedes albopictus. [7/19/2008]
Chikungunya Virus
Original source: http://microbiologybytes.wordpress.com/
Copyright information at: http://www.flickr.com/photos/ajc1/1257163357/ [7/19/2008]
Cholera in Equador
CDC This slide shows a slum in Ecuador that was heavily affected by cholera due to its proximity to unsafe water sources. [2/6/2009]
Vibrio Cholerae
This scanning electron micrograph (SEM) depicted a number of Vibrio cholerae bacteria of the serogroup 01; Magnified 22371x. CDC PHIL [1/3/2008]
Positive Tourniquet Test
CDC: This slide demonstrates what a typical positive result from a tourniquet test may look like. This patient has more than 20 petechiae per square inch. [11/23/2008]
Dengue Wideweb 470x328,0
Desperate measures: a slum area of Jakarta is sprayed with pesticide by a health [1/30/2008]
Dengue Fever Mosquito Eggs
CDC PHIL - Aedes aegypti mosquitos deposit their eggs in any container in or around houses, which can hold water. [1/30/2008]
Aedes Albopictus Female Feeding
CDC PHIL - There is a small, but significant, risk for dengue outbreaks in the continental United States. Two competent mosquito vectors, Aedes Aegypti and A. albopictus, are present and, under certain circumstances, each could transmit dengue viruses. [1/30/2008]
Disaster
Troops In Gas Masks
During a chem-bio attack alert, gas masks must be worn continuously. These US troops try to get some rest in the desert during a prolonged chem attack alert (First US Gulf war). [2/11/2009]
Hindenburg (first explosion)
The 804-foot German zeppelin Hindenburg exploded at Lakehurst Naval Air Station on May 6, 1937. This photograph is after the first explosion but before the second and third explosions. Note the two human figures atop the mooring mast. [2/11/2009]
Hindenburg
The explosion of the Hindenburg put a damper on commercial investment in rigid lighter than air devices for many years. [2/11/2009]
Crude Decontamination Station
This basic decontamination system illustrates many common flaws of poorly thought-out decontamination plans. Among other problems, the illustrated approach is slow and labor-intensive, cannot handle a mass incident, does not accomodate families, offers no provision for undressing or dressing in clean garments after decontamination, is cold, forces potentially clean patients to stand in contaminated water, and collects a small amount of runoff for no reason. [2/11/2009]
Chernobyl Robotic Inspector
The Pioneer mobile inspection robot, developed in the United States, was designed specifically in order to explore the interior of reactor No. 4 at Chernobyl after the reacter exploded in 1986. [2/11/2009]
Chernobyl
The world's worst nuclear disaster occured at the Chernobyl nuclear power station in 1986, when reactor # 4 exploded and burned. The event released massive amounts of radioactive material. The damaged reactor is seen at the right. [2/11/2009]
Ebola Microscopy
This is the classic ebola virus, with curled payload at the head. [2/11/2009]
CDC biosafety decontamination booth
In this 2007 image, Centers for Disease Control microbiologist Dr. Thomas Stevens, Jr. was showering inside a Biosafety Level 4 (BSL-4) laboratory decontamination booth, prior to exiting the sealed confines of the BSL-4 lab. The process consists of a 4 minute, 5% Microchem wash, which is followed by a 3 minute rinse with water. See PHIL 10729 for another view of this activity. [9/22/2008]
CDC Biosafety Suit
This 2007 image depicted Centers for Disease Control microbiologists Dr. Thomas Stevens, Jr., and Dr. Amy Hartman, as they were in the process of suiting up in order to access the interior of the organization’s Biosafety Level-4 (BSL-4) laboratory. Dr. Stevens was attaching his supportive air hose, which would provide a supply of filtered, breathable air, as well as maintain positive air pressure inside his air tight orange suit. [9/22/2008]
Ebola Thin Section
This micrograph shows human liver tissue infected with the Ebola virus, the cause of Ebola hemorrhagic fever. CDC PHIL [1/3/2008]
Ebola SEM
This scanning electron micrograph (SEM) depicts a number of Ebola virions. CDC PHIL [1/3/2008]
Ebola Micrograph
This negative stained transmission electron micrograph (TEM) depicts a number of filamentous Marburg virions, which had been cultured on Vero cell cultures, and purified on sucrose, rate-zonal gradients. Note the virus’s morphologic appearance with its characteristic “Shepherd’s Crook” shape; Magnified approximately 100,000x. CDC PHIL [1/3/2008]
Ebola Liver Tissue
This micrograph shows human liver tissue infected with the Ebola virus, the cause of Ebola hemorrhagic fever. CDC PHIL [1/3/2008]
Ebola Disinfection
This local Red Cross team is disinfecting a body bag of an Ebola patient in Kikwit, Democratic Republic of the Congo, 1995. CDC PHIL [1/3/2008]
Lassa Fever Map West Africa
British Medical Journal: Lassa fever: epidemiology, clinical features, and social consequences, BMJ 2003;327:1271-1275 (29 November), doi:10.1136/bmj.327.7426.1271 [2/11/2009]
P. vivax trophozoite
This thin film micrograph depicts a growing P. vivax trophozoite with conspicuous pigment granules, Magnified 1125X. [2/11/2009]
P. vivax schizont
P. vivax schizont
This thick film micrograph depicts 3 mature Plasmodium vivax schizonts, 12 merozoites, and a ring trophozoite; Magnified 1125x. [2/11/2009]
P. ovale trophozoite
This thin film micrograph depicts two P. ovale ring form trophozoites; one in rounded RBC, and one in oval RBC. [2/11/2009]
P. ovale schizont
This thin film shows an immature schizont of the parasite P. ovale along with four chromatin masses, and rounded RBCs. [2/11/2009]
P. vivax schizonts
This thick film micrograph depicts 3 mature P. vivax schizonts, 12 merozoites, and a ring trophozoite; Magnified 1125x. [2/11/2009]
P. malariae trophozoite
This thin film micrograph shows a mature, pigmented P. malariae trophozoite, stretched chromatin and irregular cytoplasm. [2/11/2009]
Negative Stain Image Of An Isolate Of Marburg
Negative stain image of an isolate of Marburg virus, showing filamentous particles as well as the characteristic "Shepherd's Crook." Magnification approximately 100,000 times. Image courtesy of Russell Regnery, Ph.D., DVRD, NCID, CDC. [2/11/2009]
Marburg Maculopapular Rash On Back
This type of maculopapular rash, which can appear on Marburg patients around the fifth day after the onset of symptoms, usually may be found on the patient’s chest, back and stomach. This patient’s skin blanched under pressure, which is a common characteristic of a Marburg virus rash. [2/11/2009]
Marburg Rash On Back
This type of maculopapular rash, which can appear on Marburg patients around the fifth day after the onset of symptoms, usually may be found on the patient’s chest, back and stomach. This patient’s skin blanched under pressure, which is a common characteristic of a Marburg virus rash. [2/11/2009]
Marburg Photomicrograph Histopathologic Changes in Liver Section
This image depicts bleeding into the hepatic sinusoids resulting from the Marburg virus. As with other hemorrhagic fevers, symptoms become increasingly severe, and may include liver failure, among other life threatening symptoms. [2/11/2009]
Marburg Pphotomicrograph Cytoarchitectural Histopathologic Changes in Kidney Sample
This slide depicts findings indicative of acute tubular necrosis (ATN), and glomerular fibrin thromboses resulting from a Marburg disease infection. Both of these are symptoms of not only Marburg virus, but other viral hemorrhagic fevers as well. [2/11/2009]
Crystal Structures Of RecA
RecA, an ubiquitous multifunctional protein, is a key component of the processes of homologous genetic recombination and DNA repair. Structural knowledge of MtRecA is imperative for a full understanding of both these activities and any ensuing application. [2/11/2009]
Green yersinia
This is a green picture of yersinia pestis. [2/11/2009]
yersinia in peripheral blood smear
The "safety pin" shape is typical of Yersinia pestis, the plague bacterium. Notice the small size of the bacteria relative to peripheral white blood cells. [2/11/2009]
yersinia fluorescent antibody test
This is a positive fluorescent antibody screen for Yersinia pestis, the plague bacterium. The classic "safety pin" shape of the bacteria can be observed even in this modality. [2/11/2009]
xenopsylla cheopsis - oriental rat flea 02
The oriental rat flea (Xenopsylla cheopis) is the primary vector of yersinia pestis (plague) in most large plague epidemics in Asia, Africa, and South America. This photo shows a large male, engorged with blood. [2/11/2009]
Bubos in plague
These bubos (massively swollen lymph nodes) are characteristic of yersinia pestis, the etiologic agent of bubonic plague. The more lethal form of the disease is pneumonic. [2/11/2009]
Plague Smear
Bubonic Plague smear demonstrating the presence of Yersinia pestis bacteria. Bipolar staining of a plague smear prepared from lymph aspirated from an adenopathic lymph node, or bubo, of plague patient. CDC PHIL [1/2/2008]
Plague Skin Hemorrhages
Seen here are small hemorrhages on the skin of a plague victim.
Capillary fragility is one of the manifestations of a plague infection, evident here on the leg of an infected patient. CDC PHIL [1/2/2008]
Axillary Bubo
An axillary bubo and edema exhibited by a plague patient. CDC PHIL [1/2/2008]
Rift Valley
Rift Valley Fever Home >
Rift Valley Fever Distribution Map January 2007
Countries with endemic disease and substantial outbreaks of RVF: Gambia, Senegal, Mauritania, Namibia, South Africa, Mozambique, Zimbabwe, Zambia, Kenya, Sudan, Egypt, Madagascar, Saudi Arabia, Yemen
Countries known to have some cases, periodic isolation of virus, or serologic evidence of RVF: Botswana, Angola, Democratic Republic of the Congo, Congo, Gabon, Cameroon, Nigeria, Central African Republic, Chad, Niger, Burkina Faso, Mali, Guinea, Tanzania, Malawi, Uganda, Ethiopia, [10/22/2008]
Rift Valley Fever Encephalitis - Rat
Replicating in an oligodendrogliocyte in the brain of a Lewis Rat that was just beginning to show signs of RVF encephalitis. [7/16/2008]
CDC - Rift Valley Fever Infected Tissue
This transmission electron micrograph (TEM) depicted a highly magnified view of a tissue that had been infected with Rift Valley fever (RVF) virus. [7/16/2008]
Sars Chest X Ray
The CXR of this health care worker shows bibasilar interstitial infiltrates and a hazy appearance in both lobes. These findings, together with high fever, respiratory distress, and a history of recent exposure to sick respiratory patients in Singapore, make this a probable case of Severe Acute Respiratory Syndrome (SARS). [2/11/2009]
Palm Civet
On May 23, 2003, Professor Yuen Kwok-yung of the University of Hong Kong microbiology department reported that he has found a coronavirus "very similar" to the SARS virus in the feces and secretions of civets found in an animal market in China's Guangdong province. Civets are captured for their fur, for their musk, and are considered a culinary delicacy in Southern China.
The common palm civet is found in temperate and tropical rainforests from Kashmir in the west to the Philippines, from China to the Sundas islands.
In Indonesia, the Palm Civet eats ripe coffee berries, and the beans within the berries are passed undigested with the feces. These coffee beans are recovered, washed, and used in coffee production. [2/11/2009]
Glomeruloid Organizing Pneumonitis in SARS (1)
When organizing pneumonitis involves an alveolus it somewhat resembles a glomerulus, hence has been called glomeruloid organizing pneumonitis. [2/11/2009]
Hand Ulcer
Hassenpfeffer is a rabbit stew popular in Germany. This is a case of tularemia. This is often caught by the handling of animal pelts such as that of a rabbit. [2/11/2009]
Amblyomma Americanum (lone star tick)
The Lone Star tick (Amblyomma Americanum) is a traditional vector for endemic Francisella tularensis, the etiologic agent of tularemia. This is one of the most infectious of the zoonoses, and can be acquired by casual exposure to infectious animal tissues or fluids, direct contact with or ingestion of contaminated water, food, or soil, and inhalation of infective aerosols. Aerosolization is common; infection and death have resulted from contact no closer than poking a dead rabbit with a walking-stick. [2/11/2009]
Tularemia Forehead
This Vermont muskrat trapper contracted tularemia, which manifested as a cutaneous lesion on his left lateral forehead. CDC PHIL [1/2/2008]
West Nile Map as of June 2003
The distribution of verified avian, animal, or mosquito infections during 2003 with additional shading for human cases, by state. If West Nile virus infection is verified in any area of a state, that entire state is shaded accordingly.
Verified cases of avian, animal or mosquito infections reported as of June 11, 2003 include: Alabama, Arkansas, Florida, Georgia, Illinois, Iowa, Kentucky, Louisiana, Michigan, Minnesota, Mississippi, New Jersey, New York, North Carolina, Pennsylvania, South Carolina, Tennessee, Wisconsin and Wyoming. [2/11/2009]
Social Crows In Tree
Crows appear to be the victims of the disease - not the critical hosts. A good host would need to maintain an intense viremia for 20-100 days, increasing the likelihood that the virus will be passed on to others. However, crows are intensely social birds, a behavior which makes them readily susceptible to infection. [2/11/2009]
Asian Tiger Mosquito - Aedes Albopicuts
More than 40 species of mosquitoes have been identified as vectors for West Nile Virus. Aedes Albopicuts, the asian tiger mosquito, is a recent arrival that has become established in ever-increasing ranges in the US. This is an aggressive biter that can attack through clothing and prefers to feed during the daylight hours. [2/11/2009]
CDC West Nile Map
Cumulative Data as of September 17, 2004.
** To ensure the confidentiality of West Nile Virus (WNV) patients in rural area, the departments of health of states indicated with this symbology have chosen not to release county level information on human WNV cases. [2/11/2009]
West Nile 2008
Map shows the distribution of avian, animal, or mosquito infection occurring during 2008 with number of human cases if any, by state. If West Nile virus infection is reported to CDC from any area of a state, that entire state is shaded. CDC [10/22/2008]
West Nile 2007
Map shows the distribution of avian, animal, or mosquito infection occurring during 2007 with number of human cases if any, by state. If West Nile virus infection is reported to CDC from any area of a state, that entire state is shaded. CDC [1/3/2008]
West Nile 2006
Map shows the distribution of avian, animal, or mosquito infection occurring during 2007 with number of human cases if any, by state. If West Nile virus infection is reported to CDC from any area of a state, that entire state is shaded. CDC [1/3/2008]
