Frequently Asked Questions (FAQ) About Tularemia
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Q. What is tularemia?
A.
Tularemia, also known as “rabbit fever,” is a disease caused by the bacterium
Francisella tularensis. Tularemia is typically found in animals,
especially rodents, rabbits, and hares. Tularemia is usually a rural disease and
has been reported in all U.S. states except Hawaii.
Q. How do
people become infected with tularemia?
A.
Typically, people become infected through the bite of infected insects (most
commonly, ticks and deerflies), by handling infected sick or dead animals, by
eating or drinking contaminated food or water, or by inhaling airborne
bacteria.
Q. Does tularemia occur naturally in the United
States?
A. Yes. Tularemia is a widespread
disease in animals. About 200 human cases of tularemia are reported each year in
the United States. Most cases occur in the south-central and western states.
Nearly all cases occur in rural areas, and are caused by the bites of ticks and
biting flies or from handling infected rodents, rabbits, or hares. Cases also
resulted from inhaling airborne bacteria and from laboratory accidents.
Q. What are the signs and symptoms of
tularemia?
A. The signs and symptoms people
develop depend on how they are exposed to tularemia. Possible symptoms include
skin ulcers, swollen and painful lymph glands, inflamed eyes, sore throat, mouth
sores, diarrhea or pneumonia. If the bacteria are inhaled, symptoms can include
abrupt onset of fever, chills, headache, muscle aches, joint pain, dry cough,
and progressive weakness. People with pneumonia can develop chest pain,
difficulty breathing, bloody sputum, and respiratory failure. Tularemia can be
fatal if the person is not treated with appropriate antibiotics.
Q. Why are we concerned about tularemia being used as a
bioweapon?
A. Francisella tularensis
is highly infectious. A small number of bacteria (10-50 organisms) can cause
disease. If Francisella tularensis were used as a bioweapon, the
bacteria would likely be made airborne so they could be inhaled. People who
inhale the bacteria can experience severe respiratory illness, including
life-threatening pneumonia and systemic infection, if they are not treated.
Q. Can someone become infected with the tularemia bacteria from
another person?
A. People have not been known
to transmit the infection to others, so infected persons do not need to be
isolated.
Q. How quickly would someone become sick if he or she were
exposed to tularemia bacteria?
A. The
incubation period (the time from being exposed to becoming ill) for tularemia is
typically 3 to 5 days, but can range from 1 to 14 days.
Q. What should someone do if he or she suspects exposure to
tularemia bacteria?
A. If you suspect you were
exposed to tularemia bacteria, see a doctor quickly. Treatment with antibiotics
for a period of 10-14 days or more after exposure may be recommended. If you are
given antibiotics, it is important to take them according to the instructions
you receive. All of the medication you are given must be taken.
Local and state health departments should be notified immediately so an investigation and infection control activities can begin.
Q. How is tularemia
diagnosed?
A. When a person has symptoms that
appear related to tularemia, the healthcare worker collects specimens, such as
blood or sputum, for testing in a diagnostic or reference laboratory. Laboratory
test results for tularemia may be presumptive or confirmatory. Presumptive
(preliminary) identification may take less than 2 hours, but confirmatory
testing will take more time, often 24 to 48 hours or longer depending on the
methods that need to be used.
Depending on the circumstances, a person may be given treatment based on symptoms before the laboratory results are returned.
Q. Can tularemia be effectively treated with
antibiotics?
A. Yes. Early antibiotic
treatment is recommended whenever it is likely a person was exposed to tularemia
or has been diagnosed as being infected with tularemia. Several types of
antibiotics have been effective in treating tularemia infections. The
tetracycline class (such as doxycycline) or fluoroquinolone class (such as
ciprofloxacin) of antibiotics are taken orally. Streptomycin or gentamicin are
also effective against tularemia, and are given by injection into a muscle or
vein. Health officials will test the bacteria in the early stages of the
response to determine which antibiotics will be most effective.
Q. How long can Francisella tularensis exist in the
environment?
A. Francisella
tularensis can remain alive for weeks in water and soil.
Q. Is there a vaccine available for
tularemia?
A. A vaccine for tularemia was used
in the past to protect laboratory workers, but it is not currently
available.
Page last modified October 8, 2003