21 October 2008

 

Botulism Countermeasures Declaration under the PREP Act made by US Government

 

In an online document dated 17 October 2008, the US Department of Health and Human Services (HHS) posted a notice in the US Federal Register (FR) by the HHS Secretary Michael O. Leavitt of a “Public Readiness and Emergency Preparedness Act (PREP) Act Declaration Regarding Botulism Countermeasures.”  Find this link at: http://www.hhs.gov/disasters/discussion/planners/prepact/index.html

 

 

This HHS website, dedicated to the Public Readiness and Emergency Preparedness (PREP) act states that:

“A PREP Act declaration is specifically for the purpose of providing immunity from tort liability, and is different from, and not dependent on, other emergency declarations.”

 

In addition, “The PREP Act authorizes the Secretary of the Department of Health and Human Services (“Secretary”) to issue a declaration (“PREP Act Declaration”) that provides immunity from tort liability (except for willful misconduct) for claims of loss caused, arising out of, relating to, or resulting from administration or use of countermeasures to diseases, threats and conditions determined by the Secretary to constitute a present, or credible risk of a future public health emergency to entities and individuals involved in the development, manufacture, testing, distribution, administration, and use of such countermeasures.”

 

The US Federal Register official notice of this Botulism Countermeasure PREP act Declaration by HHS Secretary Leavitt is dated October 17, 2008 (Volume 73, Number 202) pages 61864-61866.

 

The Botulinum toxin covered countermeasures under this PREP Act Declaration are defined under section IX in this Federal Register document by Secretary Leavitt to include “any vaccine; antimicrobial/antibiotic, or other drug or antitoxin; or diagnostic or device to identify, prevent or treat botulinum toxin or adverse events from such countermeasures (1) licensed under section 351 of the public Health Service Act; (2) approved under section 505 or section 515 of Federal the Food, Drug, and Cosmetic Act (FDCA); (3) ….” The full Federal Register notice can be found online at: http://edocket.access.gpo.gov/2008/E8-24734.htm

 

 

Appendix I to this document lists five U.S. government Contracts as covered countermeasures for this PREP Act declaration:

 

“Covered Countermeasure”                  

Manufacturer

 

 

Heptavalent antitoxin

Cangene

Heptavalent antitoxin

PerImmune

 

 

Heptavalent antitoxin,

Cangene

Monovalent E

 

 

 

Monovalent E

Aventis Pasteur

Bivalent A and B

Aventis Pasteur

 

 

 

Similar PREP Act Declarations were made for anthrax countermeasures on October 1, 2008, as well as on October 17, 2008 for smallpox countermeasures, pandemic influenza antivirals, and acute radiation syndrome countermeasures.

 

 

 

Daniel R. Lucey, MD, MPH

EROne Institutes, Department of Emergency Medicine

Washington Hospital Center

Adjunct Professor of Microbiology and Immunology

Georgetown University Medical Center

Washington, D.C.

Website for this posting: www.BePast.org

E-mail:DRL23@Georgetonw.edu