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<div class=3DSection1>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:12.0=
pt;
font-family:Arial'>11 Nov 2008<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:12.0=
pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><b style=3D'mso-bidi-font-weight:normal'><span
style=3D'mso-bidi-font-size:14.0pt;font-family:Arial;mso-bidi-font-family:"=
Times New Roman"'>Sporadic
Flu Activity Reported in DC and 15 states: <o:p></o:p></span></b></p>

<p class=3DMsoNormal><b style=3D'mso-bidi-font-weight:normal'><span
style=3D'mso-bidi-font-size:14.0pt;font-family:Arial;mso-bidi-font-family:"=
Times New Roman"'>No
Shortage of New Trivalent Flu Vaccine<o:p></o:p></span></b></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial;mso-bidi-font-family:"Times New Roman"'><o:p>&nbsp;</o:p>=
</span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>The most recent CDC update on influenza (flu) activity in
the USA for week 44, ending November 1 reports sporadic activity in Washing=
ton,
DC, Puerto Rico and 15 states: Alaska, California, Colorado, Connecticut,
Delaware, Hawaii, Idaho, Illinois, Indiana, Massachusetts, Nevada, New York,
Pennsylvania, Texas, and Utah. So far, the proportion of outpatient visits =
due
to Influenza-Like-Illness (<st1:stockticker w:st=3D"on">ILI</st1:stockticke=
r>)
remains below national and region-specific baseline levels.<o:p></o:p></spa=
n></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>The three components of this year&#8217;s annual flu vac=
cine
are all different than last year&#8217;s flu vaccine, based on the best
assessment of what strains of Influenza A (H1N1 and H3N2) and Influenza B a=
re most
likely to be circulating this year. The current 2008-2009 trivalent vaccine
virus strains are:<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>---Influenza A/ Brisbane/59/2007 (H1N1)-like<o:p></o:p><=
/span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>---Influenza A/Brisbane/10/2007 (H3N2)-like<o:p></o:p></=
span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>---Influenza B/Florida/4/2006-like antigens.<o:p></o:p><=
/span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>No shortage of influenza vaccine in this country is expe=
cted
this year. This is true even though starting this 2008-2009 season all young
persons ages 5-18 years have been added to the list of those recommended to
receive the annual flu vaccine.<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>Now is a good time to receive the flu vaccine in order to
develop protective immunity before influenza viruses become more widespread=
 in
the <st1:country-region w:st=3D"on"><st1:place w:st=3D"on">US</st1:place></=
st1:country-region>
and elsewhere in the northern hemisphere. <span
style=3D'mso-spacerun:yes'>&nbsp;</span>The emergence of oseltamivir
(Tamiflu)-resistant influenza<span style=3D'mso-spacerun:yes'>&nbsp; </span=
>A
(H1N1) viruses will continue to be monitored closely in the USA after their
appearance last January in Europe and during the flu season several months =
ago
in the southern hemisphere e.g., in South Africa.<o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>Daniel R. Lucey, MD, <st1:stockticker w:st=3D"on">MPH</s=
t1:stockticker><o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>EROne Institutes, Department of Emergency Medicine<o:p><=
/o:p></span></p>

<p class=3DMsoNormal><st1:place w:st=3D"on"><st1:PlaceName w:st=3D"on"><span
  style=3D'font-size:9.0pt;mso-bidi-font-size:14.0pt;font-family:Arial'>Was=
hington</span></st1:PlaceName><span
 style=3D'font-size:9.0pt;mso-bidi-font-size:14.0pt;font-family:Arial'> <st=
1:PlaceType
 w:st=3D"on">Hospital</st1:PlaceType> <st1:PlaceType w:st=3D"on">Center</st=
1:PlaceType></span></st1:place><span
style=3D'font-size:9.0pt;mso-bidi-font-size:14.0pt;font-family:Arial'><o:p>=
</o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>Website for this posting: <a href=3D"http://www.bepast.o=
rg/">www.BePast.org</a><o:p></o:p></span></p>

<p class=3DMsoNormal><span style=3D'font-size:9.0pt;mso-bidi-font-size:14.0=
pt;
font-family:Arial'>e-mail:Daniel.R.Lucey@Medstar.net<o:p></o:p></span></p>

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